EP 4298127 A1 20240103 - ANTIBODY FUSION PROTEINS TARGETING IL-6 RECEPTOR AND ANGIOGENIC FACTORS
Title (en)
ANTIBODY FUSION PROTEINS TARGETING IL-6 RECEPTOR AND ANGIOGENIC FACTORS
Title (de)
ANTIKÖRPERFUSIONSPROTEINE ZUM TARGETING DES IL-6-REZEPTORS UND ANGIOGENER FAKTOREN
Title (fr)
PROTÉINES DE FUSION D'ANTICORPS CIBLANT LE RÉCEPTEUR IL-6 ET FACTEURS ANGIOGÉNIQUES
Publication
Application
Priority
- US 202163207444 P 20210227
- CN 2022076673 W 20220217
Abstract (en)
[origin: WO2022179432A1] An antibody fusion protein comprises an antibody against IL-6 receptor or an antigen-binding fragment thereof linked to a VEGF binding unit comprising a plurality of Ig-like domains of a first VEGF receptor, a second human VEGF receptor, and/or a third human VEGF receptor. The antibody fusion protein is useful in treating or controlling an ocular disease, condition, or disorder that has etiology in aberrant angiogenesis or inflammation.
IPC 8 full level
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61P 27/02 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP KR)
A61P 27/02 (2017.12 - EP KR); A61P 35/00 (2017.12 - EP KR); C07K 14/71 (2013.01 - EP KR); C07K 16/2866 (2013.01 - EP KR); A61K 2039/505 (2013.01 - KR); C07K 2317/622 (2013.01 - EP KR); C07K 2317/76 (2013.01 - EP KR); C07K 2317/92 (2013.01 - EP KR); C07K 2319/00 (2013.01 - EP KR); C07K 2319/31 (2013.01 - EP); C07K 2319/32 (2013.01 - EP KR)
Citation (search report)
See references of WO 2022179432A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2022179432 A1 20220901; AU 2022227047 A1 20230914; CA 3211803 A1 20220901; CN 116897165 A 20231017; EP 4298127 A1 20240103; JP 2024507397 A 20240219; KR 20230150858 A 20231031; MX 2023009956 A 20230905; TW 202246359 A 20221201
DOCDB simple family (application)
CN 2022076673 W 20220217; AU 2022227047 A 20220217; CA 3211803 A 20220217; CN 202280017398 A 20220217; EP 22758797 A 20220217; JP 2023551991 A 20220217; KR 20237033126 A 20220217; MX 2023009956 A 20220217; TW 111106352 A 20220222