EP 4308690 A1 20240124 - IMMUNE CELL WHICH HAS AN FC RECEPTOR ON ITS SURFACE AND TO WHICH IS GRAFTED A HYBRID MOLECULE COMPRISING AN ANTIBODY FC FRAGMENT AND AT LEAST ONE FIBRIN-DERIVED CITRULLINE PEPTIDE, AND USES THEREOF
Title (en)
IMMUNE CELL WHICH HAS AN FC RECEPTOR ON ITS SURFACE AND TO WHICH IS GRAFTED A HYBRID MOLECULE COMPRISING AN ANTIBODY FC FRAGMENT AND AT LEAST ONE FIBRIN-DERIVED CITRULLINE PEPTIDE, AND USES THEREOF
Title (de)
IMMUNZELLE MIT EINEM FC-REZEPTOR AUF IHRER OBERFLÄCHE UND MIT EINEM HYBRIDMOLEKÜL MIT EINEM ANTIKÖRPER-FC-FRAGMENT UND EINEM CITRULLINPEPTID AUS FIBRIN
Title (fr)
CELLULE IMMUNITAIRE COMPRENANT UN RECEPTEUR FC A SA SURFACE, ET SUR LEQUEL EST GREFFE UNE MOLECULE HYBRIDE COMPRENANT UN FRAGMENT FC D'ANTICORPS ET AU MOINS UN PEPTIDE CITRULLINE DERIVE DE LA FIBRINE, ET SES UTILISATIONS
Publication
Application
Priority
- FR 2102805 A 20210319
- FR 2022050506 W 20220318
Abstract (en)
[origin: WO2022195239A1] The invention relates to an immune cell comprising at least one Fc receptor on its surface, characterised in that a hybrid molecule is grafted at the Fc receptor, said hybrid molecule comprising at least one antibody Fc fragment covalently bound to at least one fibrin-derived peptide comprising one or more citrullyl residue(s). The present invention also relates to the uses of such a grafted cell and the method for producing same.
IPC 8 full level
C12N 5/0783 (2010.01); A61K 35/15 (2015.01); A61K 35/17 (2015.01); A61P 19/02 (2006.01); A61P 37/00 (2006.01); C07K 14/47 (2006.01); C07K 14/735 (2006.01); C07K 14/75 (2006.01); C12N 5/0786 (2010.01)
CPC (source: EP US)
A61K 39/4613 (2023.05 - EP US); A61K 39/4614 (2023.05 - EP US); A61K 39/4621 (2023.05 - US); A61K 39/4622 (2023.05 - EP US); A61K 39/46433 (2023.05 - US); A61K 39/4644 (2023.05 - EP US); A61P 19/02 (2018.01 - EP); A61P 37/00 (2018.01 - EP); C07K 14/70535 (2013.01 - EP US); C07K 14/75 (2013.01 - EP US); C12N 5/0645 (2013.01 - EP US); C12N 5/0646 (2013.01 - EP US); A61K 38/00 (2013.01 - EP); C07K 2319/30 (2013.01 - US); C12N 2510/00 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
FR 3120877 A1 20220923; EP 4308690 A1 20240124; US 2024307538 A1 20240919; WO 2022195239 A1 20220922
DOCDB simple family (application)
FR 2102805 A 20210319; EP 22715349 A 20220318; FR 2022050506 W 20220318; US 202218551156 A 20220318